Associate Scientist or Scientist I Molecular Function
AI-first protein-design company using generative foundation models and wet-lab validation to create functional proteins and genome-editing systems.
Funding history
About Profluent
Profluent develops AI models for de novo protein design, with applications in biomedicine, agriculture, and industrial biology. Its platform includes protein-generation models such as ProGen3 and the AI-designed OpenCRISPR-1 gene editor.
Skills
Candidate Availability
Required and preferred rules are kept separate and reflect the wording in the original posting.
About the Role
You will lead phage display campaigns and build high-throughput platforms for measuring protein-protein interactions. You will develop assays, establish quality controls, analyze screening outputs, and work with scientific partners to produce model-ready binding datasets.
Requirements
- MS with 3+ years of industry experience or PhD with 0–2 years of industry experience in a relevant discipline
- Hands-on phage display and antibody discovery experience
- Molecular biology skills for library construction
- NGS-based screening knowledge
- Ability to turn sequencing data into quantitative measurements
- Analytical and troubleshooting skills
- Record-keeping
Responsibilities
- Build high-throughput platforms for identifying and measuring protein-protein interactions
- Lead phage display campaigns from library construction through panning, NGS, and hit validation
- Design and troubleshoot selection strategies, antigen selection, library QC, and stringency selections
- Plan campaigns with machine learning and protein design scientists
- Define binding-data requirements for model training and evaluation
Benefits
- Equity participation
- 401(k) employer match
- Health insurance
- Dental insurance
- Vision insurance
- Generous PTO