Senior Scientist AI Assisted Lab Optimization

SecureBio is a U.S. 501(c)(3) nonprofit that develops pandemic-defense capabilities and evaluates AI-enabled biological risks.

Recently fundedCompany intelligence
Cambridge, MA, United States
About SecureBio

SecureBio operates pathogen-agnostic early-warning work through deep metagenomic sequencing and builds evaluations and mitigations for biosecurity-relevant frontier-AI capabilities.

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Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will lead an AI-in-the-loop wet-lab R&D program from experimental design through execution, analysis, and documentation. You will optimize molecular protocols, use frontier AI tools in experimental work, build quality-control feedback loops, benchmark results, maintain lab records, and produce a documented AI-uplift case study.

Requirements

  • PhD in molecular biology, microbiology, bioengineering, or a related field, or an MS with equivalent hands-on experience
  • Hands-on expertise in viral enrichment, nucleic acid extraction, NGS library preparation, and protocol development
  • Experience optimizing and troubleshooting complex molecular protocols
  • Experimental design and quantitative data analysis skills
  • Fluency using frontier AI tools in scientific work
  • Communication and collaboration skills
  • Ability to independently own a research program

Responsibilities

  • Identify optimization experiments for viral enrichment, depletion, extraction, and sequencing library preparation
  • Use frontier AI models to propose protocol modifications, structure experiments, and interpret outputs
  • Execute and coordinate wet-lab experiments
  • Build QC feedback loops using sequencing reports and protocol metadata
  • Benchmark results using reproducible metrics and controls
  • Design a logging, labeling, and annotation approach for AI interactions
  • Produce a documented case study of AI uplift in wet-lab work
  • Maintain electronic lab notebooks and rigorous QA/QC
  • Help laboratory colleagues use AI tools effectively

Benefits

  • Health, dental, and vision insurance
  • Yearly mental health allowance
  • Flexible work hours
  • Unlimited paid time off
  • Minimum 12 weeks of fully paid parental leave
  • Fully paid conference sponsorships
  • Yearly development allowance
  • Employer 401(k) match up to 4% of total salary
  • Ergonomic office equipment
  • Snacks and daily catered lunches