Senior Research Associate - Technology Development
AI-first protein-design company using generative foundation models and wet-lab validation to create functional proteins and genome-editing systems.
Funding history
About Profluent
Profluent develops AI models for de novo protein design, with applications in biomedicine, agriculture, and industrial biology. Its platform includes protein-generation models such as ProGen3 and the AI-designed OpenCRISPR-1 gene editor.
Skills
Candidate Availability
Required and preferred rules are kept separate and reflect the wording in the original posting.
About the Role
You will develop and scale mammalian cell-based gene-editing assays, plasmid cloning campaigns, and DNA libraries. You will use automated workflows and readouts such as flow cytometry and next-generation sequencing, analyze experimental data, present results, maintain accurate records, and support laboratory operations and EHS standards.
Requirements
- BS in Molecular Biology, Biochemistry, Cell Biology, or a related field with 4 years of relevant industry research experience, or MS in a related field with 2 years of relevant industry research experience
- Extensive hands-on experience with mammalian and bacterial cell culture and molecular biology
- Experience with flow cytometry
- Excellent communication skills and ability to collaborate across interdisciplinary teams
- Strong organizational skills for tracking laboratory samples and experimental data
Responsibilities
- Develop, execute, and automate arrayed and pooled mammalian cell-based gene-editing assays
- Design and execute low- and high-throughput plasmid cloning campaigns to construct DNA libraries
- Use plate-based assays, flow cytometry, and next-generation sequencing readouts
- Perform mammalian cell culture and transfection
- Track and document experimental samples, assay data, and results
- Analyze experimental data and interpret results
- Present experimental results in team and cross-team meetings
- Contribute to laboratory maintenance and adhere to EHS standards
Benefits
- Equity participation
- 401(k) with employer match
- Health, dental, and vision insurance
- Generous PTO policy
- Work-life balance