Senior Associate Scientist I II Purification Sciences

Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.

San Diego, United States
About Iambic Therapeutics

Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.

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Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will perform small-molecule purification using preparative LC and SFC, optimize purification methods, operate analytical systems, and conduct quality control. You will maintain and troubleshoot instruments, support high-throughput workflows, deliver purified compounds, and maintain laboratory documentation.

Requirements

  • B.S. or M.S. in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related discipline with 3+ years of experience
  • Hands-on laboratory experience in chromatography and small-molecule purification
  • Knowledge of chromatographic separation principles and method optimization
  • Problem-solving skills

Responsibilities

  • Perform small-molecule purification using preparative LC and SFC
  • Develop and optimize purification methods
  • Operate preparative LC, preparative SFC, analytical LC, and LC/MS systems
  • Perform analytical QC of purified compounds
  • Perform instrument maintenance and troubleshoot chromatography issues
  • Monitor instrument performance and identify issues
  • Support high-throughput and automated purification workflows
  • Prioritize samples and deliver purified compounds
  • Support new purification methods, instrumentation, and workflow improvements
  • Maintain experimental and instrument documentation

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401K matching
  • Uncapped vacation
  • Onsite gym
  • Onsite dining