Research Scientist I II Purification Sciences

Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.

San Diego, United States
About Iambic Therapeutics

Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.

View jobs by Iambic Therapeutics

Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will develop and execute small-molecule purification strategies using preparative SFC and LC. You will solve complex separations, support compound quality control, troubleshoot and maintain instruments, improve automated workflows, and deliver purified compounds and analytical data.

Requirements

  • Ph.D. in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related discipline with 0–5 years of relevant experience, or an M.S. with 7+ years or B.S. with 9+ years of relevant experience
  • Expertise in small-molecule chromatographic purification and method development
  • Expertise in preparative SFC method development, optimization, and troubleshooting
  • Understanding of chromatographic separation science
  • Instrument troubleshooting skills
  • Understanding of medicinal chemistry and small-molecule drug discovery
  • Scientific problem-solving, communication, and collaboration skills

Responsibilities

  • Develop and execute small-molecule purification strategies using preparative SFC and LC
  • Solve challenging separations through chromatographic method optimization
  • Develop high-throughput compound QC workflows using LC/MS
  • Establish purification and QC strategies with medicinal chemistry and HTE teams
  • Troubleshoot SFC/LC purification and analytical QC instruments
  • Support SFC, LC, and LC/MS platforms through maintenance and optimization
  • Develop automated high-throughput purification and QC workflows
  • Evaluate and implement chromatography, analytical, automation, and informatics technologies

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401K matching
  • Uncapped vacation
  • Onsite gym
  • Onsite dining