Research Scientist I/II in Immunology

Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.

San Diego, United States
About Iambic Therapeutics

Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.

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Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will design, optimize, and execute immunology assays using relevant cells and tissues. You will analyze compound-profiling data, support in vivo studies and assay transfers, maintain laboratory records, and communicate results and recommendations to project teams.

Requirements

  • PhD in immunology or a related field with 0–4 years of relevant experience, or an MS with 7+ years or BS with 9+ years of relevant experience
  • Knowledge of innate and/or adaptive immunology and immune-cell signaling
  • Experience with primary human or animal immune cells, whole blood, or tissue-based systems
  • Proficiency in multiparameter flow cytometry, cytokine or chemokine assays, and functional or molecular readouts
  • Ability to develop and troubleshoot cell-based assay cascades
  • Experience supporting small-molecule discovery through compound screening or profiling
  • Working knowledge of in vivo immunology, pharmacology, PK/PD, and pharmacodynamic biomarkers

Responsibilities

  • Design, optimize, troubleshoot, and execute in vitro and ex vivo immunology assays
  • Run recurring compound-profiling assays and generate reproducible data
  • Analyze concentration-response relationships, assay performance, reproducibility, and biological relevance
  • Maintain electronic laboratory records, protocols, and data packages
  • Support in vivo immunology studies, sample processing, ex vivo analyses, and data interpretation
  • Support assay transfer and external studies with CROs or collaborators
  • Contribute to laboratory operations, reagent and instrument qualification, and method documentation

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401(k) matching
  • Uncapped vacation
  • Onsite gym
  • Onsite dining