Research Scientist I II Bioanalytical Sciences and Assay Development
Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.
Funding history
About Iambic Therapeutics
Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.
Skills
Candidate Availability
Required and preferred rules are kept separate and reflect the wording in the original posting.
About the Role
You will develop and implement mass spectrometry-based assays and screening workflows for hit identification, compound characterization, and ADME/DMPK. You will optimize LC-MS/MS methods, automate high-throughput workflows, troubleshoot instrumentation, generate experimental data, and collaborate on assay strategies.
Requirements
- Ph.D. in Bioanalytical Chemistry, Mass Spectrometry, Chemical Biology, Drug Metabolism/Pharmacokinetics, Pharmaceutical Sciences, Biochemistry, or a related discipline with approximately 0–5 years of relevant experience, or an M.S. with significant relevant industry experience
- Foundation in mass spectrometry, bioanalytical science, and assay development
- Experience developing, optimizing, and troubleshooting bioanalytical, biochemical, or screening assays
- Understanding of quantitative assay design, experimental controls, data quality, and troubleshooting
- Scientific problem-solving and collaboration skills
Responsibilities
- Develop and implement MS-based assays and screening workflows for hit identification
- Develop bioanalytical and biochemical assays for screening, hit confirmation, and compound characterization
- Develop and execute in vitro ADME/DMPK assays
- Develop physicochemical property assays
- Develop and optimize LC-MS/MS bioanalytical methods
- Develop automated and high-throughput assay workflows
- Support operation and troubleshooting of MS and LC/MS instrumentation
- Generate experimental datasets for AI/ML-driven compound design
- Collaborate on assay strategies and experimental insights
- Evaluate assay technologies, MS methodologies, automation solutions, and data workflows
Benefits
- Company-paid healthcare
- Flexible spending accounts
- Voluntary life insurance
- 401K matching
- Uncapped vacation
- Onsite gym
- Onsite dining