Principal AI Scientist Polytope Bio

A 501(c)(3) science-and-technology research institute/foundation operating direct Neuro-AI research, life-sciences programs through Radial, and an open-science residency program.

Emeryville, CA, United States
About Astera Institute

Astera Institute supports and operates open public-goods work for science and technology. Its current activities include neuroscience-informed AGI research, AI-enabled life-sciences programs, open datasets and publishing infrastructure, and residencies for early-stage projects.

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Skills

About the Role

You will co-direct the AI research program with the founder, shaping research direction and technical execution. You will develop reinforcement-learning post-training methods, build and debug model training infrastructure and evaluation metrics, and align biological measurements with model learning.

Requirements

  • Machine learning
  • Computational biology
  • Model training
  • Diffusion model
  • Transformer
  • Reinforcement learning
  • Preference optimization
  • Deep learning

Responsibilities

  • Co-direct the research program with the founder
  • Develop reinforcement-learning feedback loops for biological language models
  • Architect model training infrastructure
  • Build, run, and debug models, training loops, and evaluation metrics
  • Partner with the experimental team to align measurements and model learning

Benefits

  • Health insurance
  • Company-sponsored retirement plan
  • Vision coverage
  • Dental coverage
  • Dedicated GPU resources