Bioanalytical Lead
Isomorphic LabsVisit Isomorphic Labs website
AI-first drug design and development company building a unified drug-design engine to advance new medicines.
London, United Kingdom
Funding history
Investors
About Isomorphic Labs
Isomorphic Labs uses predictive and generative AI models, computational biology, and drug-design expertise to develop therapeutics across partnered and internal programs.
Skills
Candidate Availability
Required and preferred rules are kept separate and reflect the wording in the original posting.
About the Role
You will define and execute bioanalytical strategies across small molecules, biologics, and ADCs. You will oversee assay development and external laboratories, manage CROs and global sample logistics, integrate data into predictive models, and author regulatory bioanalytical documentation.
Requirements
- PhD with 5+ years of biotech or pharmaceutical industry experience, or BS/MS with 8+ years of equivalent experience
- Experience leading bioanalytical strategies for small molecules, biologics, and ADCs
- Understanding of GLP and non-GLP regulations, FDA and EMA validation guidelines, and ICH guidelines
- Experience with LC-MS/MS, LBA, and flow cytometry
- Experience developing and validating biomarker assays
- Knowledge of global sample shipping logistics, biosafety regulations, and chain of custody
- Experience writing bioanalytical sections for successful IND submissions
Responsibilities
- Define and execute bioanalytical strategies across therapeutic modalities
- Oversee PK, PD, and immunogenicity assay design, validation, and transfer
- Collaborate with machine learning scientists to integrate bioanalytical data into predictive models
- Lead biomarker assay strategies
- Select, qualify, and manage global CRO partners
- Manage international sample shipments, cold-chain logistics, compliance, and stability tracking
- Troubleshoot complex assay anomalies
- Author and review bioanalytical sections of IND applications and investigator brochures
- Represent bioanalysis in cross-functional teams and regulatory-agency interactions