Young Investigator Open Language Models for Biology

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Seattle-based nonprofit AI research institute developing fully open models, datasets, tools, and applied AI systems for scientific discovery, the planet, and robotics.

Seattle, United States
About Allen Institute for AI (Ai2)

Ai2 builds breakthrough AI around an open-development approach, publishing model weights, training code, training data, recipes, evaluations, and documentation. Its current work includes the Olmo language-model family, Molmo multimodal models, Tülu post-training models, the Asta scientific-agent ecosystem, and AI-for-the-planet products.

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Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will develop multimodal language models that combine single-cell gene-expression data with text. You will reproduce, evaluate, and improve relevant approaches for brain and neurodegeneration data; design controlled experiments; develop donor and brain-region representations; interpret results with scientists; and release research artifacts for publication.

Requirements

  • Completed PhD or PhD expected within one year in machine learning, computational biology, computational neuroscience, physics, or a related quantitative field
  • Experience training or fine-tuning transformer-based language models
  • Python skills
  • PyTorch skills
  • Experience writing reliable, reproducible research code
  • Ability to conduct independent research on open-ended problems
  • Ability to communicate clearly with machine-learning researchers and biological scientists

Responsibilities

  • Develop a multimodal language model combining single-cell gene-expression data with text
  • Reproduce and evaluate relevant approaches, including scGPT, Geneformer, CellWhisperer, and C2S-Scale
  • Adapt and improve approaches for brain and neurodegeneration data
  • Design controlled experiments comparing language-grounded models with baselines
  • Develop brain-region and donor-level representations incorporating pathology and disease progression
  • Evaluate models on held-out donors
  • Interpret results and identify predictions for experimental follow-up
  • Release data, code, and model weights and prepare results for publication

Benefits

  • Medical, dental, vision, and employee assistance program coverage for team members and families
  • Health savings account, healthcare reimbursement arrangement, and healthcare and dependent-care flexible spending accounts
  • 401k plan
  • $125 per month for commuting or internet expenses
  • $200 per month for fitness and wellbeing expenses
  • Up to 10 sick days, 7 personal days, 20 vacation days, and 12 paid holidays per year
  • Annual bonuses
  • Family leave
Young Investigator Open Language Models for Biology at Allen Institute for AI (Ai2) | JobStash