Senior Associate Scientist I or II Medicinal Chemistry

Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.

San Diego, United States
About Iambic Therapeutics

Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.

View jobs by Iambic Therapeutics

Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will design, synthesize, purify, and characterize chemical compounds using modern analytical techniques and individual or automated parallel synthesis. You will optimize reactions, support high-throughput experiments, analyze biological and ADME-PK data, apply machine-learning insights, and present results and recommendations to project teams and senior leadership.

Requirements

  • BS in Chemistry with 5+ years of pharmaceutical or biotechnology experience, or MS in Chemistry with 3+ years of pharmaceutical or biotechnology experience
  • Multi-step organic synthesis
  • Reaction optimization
  • SAR analysis
  • Scientific presentation
  • Availability to work onsite in San Diego
  • High-throughput experimentation
  • ADME-PK principles
  • Drug discovery
  • Molecular modeling
  • Structure-based drug design

Responsibilities

  • Design, synthesize, purify, and characterize chemical compounds
  • Use LCMS, HPLC, and NMR for compound analysis
  • Apply individual and automated parallel synthesis approaches
  • Identify and optimize reaction conditions
  • Collaborate on high-throughput parallel chemistry experiments
  • Analyze biological and ADME-PK data using cheminformatics tools
  • Apply machine-learning insights to the design–make–test cycle
  • Present results, implications, and recommendations to project teams and senior leadership

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401K matching
  • Uncapped vacation
  • Onsite gym
  • Onsite dining