Senior Associate Scientist I or II in Medicinal Chemistry

Clinical-stage life-science and technology company that develops medicines using an AI-driven discovery and development platform.

San Diego, United States
About Iambic Therapeutics

Iambic Therapeutics combines proprietary AI technologies, including Enchant and NeuralPLexer, with automated chemistry and biology experimentation to discover and develop small-molecule medicines. Its current pipeline includes clinical and preclinical oncology candidates.

View jobs by Iambic Therapeutics

Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will design, synthesize, purify, and characterize chemical compounds using modern analytical methods. You will optimize reactions, support parallel chemistry experiments, analyze biological and ADME-PK data, use machine-learning insights, and present findings and recommendations.

Requirements

  • BS in chemistry with 5+ years of pharma or biotech experience, or MS in chemistry with 3+ years of pharma or biotech experience
  • Skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation
  • Availability to work onsite in San Diego

Responsibilities

  • Design, synthesize, purify, and characterize chemical compounds at 10 mg to 5 g scale
  • Use LCMS, HPLC, and NMR for compound analysis
  • Identify and optimize reaction conditions using screening kits and streamlined methods
  • Collaborate on parallel chemistry and high-throughput experimentation
  • Analyze biological and ADME-PK data using cheminformatics tools
  • Partner with computational chemists to use machine-learning insights in design–make–test cycles
  • Present data, implications, and recommendations to project teams and senior leadership

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401(k) matching
  • Uncapped vacation
  • Onsite gym
  • Onsite dining