Senior Software Engineer (LLM Engineering)

AI-first drug design and development company building a unified drug-design engine to advance new medicines.

Series BRecently funded
London, United Kingdom
About Isomorphic Labs

Isomorphic Labs uses predictive and generative AI models, computational biology, and drug-design expertise to develop therapeutics across partnered and internal programs.

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Skills

Candidate Availability

Required and preferred rules are kept separate and reflect the wording in the original posting.

About the Role

You will architect, implement and own systems that bring LLMs into scientific and business processes. You will build robust and scalable generative AI infrastructure, agentic tooling, evaluation frameworks and observability, and partner with researchers to turn scientific needs into technical specifications.

Requirements

  • Strong Python coding skills for production-grade systems
  • Ability to architect and maintain complex cloud systems with IaC
  • Deep understanding of LLM internals and limitations
  • Experience with LLM serving stack (e.g. vLLM)
  • Experience evaluating probabilistic ML systems and managing tool use and contexts
  • First-principles problem solving
  • Excellent stakeholder management and communication

Responsibilities

  • Architect LLM-integrated systems with scalability, security and UX in mind
  • Enable telemetry, observability, governance and cost management
  • Implement context management, tool-use (MCP), skill tooling and RAG
  • Build and maintain evals for probabilistic systems
  • Develop agentic tooling and IDE integrations
  • Support fine-tuning and RL efforts with AI researchers
  • Partner with researchers and business teams to unlock LLM use-cases