Research Investigator / Senior Research Investigator (In-vitro Pharmacology, Exploratory Sciences)
Isomorphic LabsVisit Isomorphic Labs website
AI-first drug design and development company building a unified drug-design engine to advance new medicines.
Series BRecently funded
London, United Kingdom
Funding history
Investors
About Isomorphic Labs
Isomorphic Labs uses predictive and generative AI models, computational biology, and drug-design expertise to develop therapeutics across partnered and internal programs.
Skills
Candidate Availability
Required and preferred rules are kept separate and reflect the wording in the original posting.
About the Role
You will be the experimental engine behind exploratory programmes, designing, building and running assays that show whether new modalities work. You will generate high-quality ML-ready data, use LLM agentic workflows, and work with chemistry, DMPK and computational colleagues and CROs.
Requirements
- BSc, MSc or PhD in pharmacology, biochemistry, biophysics, cell biology or related
- Extensive experience designing biological screening cascades
- Strong hands-on in vitro pharmacology and/or biophysics expertise
- Experience or interest in novel modalities
- Experience or enthusiasm for LLM agentic workflows
- Collaborative and adaptable
- Clear communication across disciplines
Responsibilities
- Design, develop and run biochemical, biophysical and cellular assays for novel modalities
- Generate quantitative data on binding kinetics, ternary complexes, degradation and pathway readouts
- Develop cellular assays showing target engagement
- Profile novel chemical matter and interpret results
- Build and refine screening cascades
- Generate reproducible ML-ready datasets
- Use LLM agentic workflows and in silico tools
- Coordinate CRO wet-lab studies
- Present results to project teams
- Represent the company externally